Difference between revisions of "Teleost Anatomy Ontology"

From phenoscape
Jump to: navigation, search
(Anatomy Term Trackers)
(Anatomy Term Trackers)
Line 16: Line 16:
 
**ceratobranchial 5 tooth is_a multi-tissue structure
 
**ceratobranchial 5 tooth is_a multi-tissue structure
  
===Anatomy Term Trackers===
+
===Anatomy Term Tracker===
  
Term requests should include the name of the term being requested, its definition in [[Guide_to_Character_Annotation#Genus-differentia_definitions|genus-differentia form]], any known synonyms, and all relevant relationships of the term with other existing terms.
+
The anatomy ontology is regulary updated to include new terms and developed based on feedback from the community. Requests for changes are submitted to the anatomy term tracker and a summary is forwarded to the teleost-discuss mailing list for community discussion (see [[Term Requests | instructions on requesting terms]] for details). Terms are added to the TAO usually within one week, with any comments or suggestions from  teleost-discuss incorporated. We invite you to join the teleost-discuss mailing list and contribute to the discussion of terms.
 
+
If a term applies to zebrafish and teleost fishes, it should be submitted to [http://sourceforge.net/tracker/?group_id=76834&atid=994726 Zebrafish anatomy tracker].  If a term does not apply zebrafish, submit the request to [http://sourceforge.net/tracker/?group_id=76834&atid=994764 Teleost anatomy tracker].  Submitted requests are forwarded from the tracker to the [https://lists.sourceforge.net/lists/listinfo/obo-teleost-discuss Teleost-discuss mailing list] and terms are added to the TAO usually within one week, with any comments or suggestions from  teleost-discuss incorporated. We invite you to join the teleost-discuss mailing list and contribute to the discussion of terms.
+
  
 
===Homology===
 
===Homology===

Revision as of 17:55, 10 July 2008

The Teleost Anatomy Ontology (TAO) is a multi-species anatomy ontology for ostariophysan fishes. Growth of the TAO is enabled by contributions from data curators and the ichthyological community (see Anatomy Term Trackers). The TAO can be browsed by using the NCBO BioPortal.

TAO and ZFA synchronization

The TAO was initialized with terms from the ZFA, and we currently maintain manual synchronization of the two ontologies. A synchronization tool (in development) will help automate this process.

One of the challenges in synchronzing the two ontologies involves the addition of terms to the TAO that are not required for the ZFA. The addition of these terms to the TAO may require the creation of additional intermediate terms that are redundant for the ZFA. For example, zebrafish have only one type of tooth (ceratobranchial 5 tooth). Other teleost species have teeth on the jaw bones and other branchial arch and oral cavity bones. Because of this, the term ‘tooth’ is needed in the TAO as a parent to all tooth types:

  • TAO:
    • ceratobranchial 5 tooth is_a tooth
    • premaxillary tooth is_a tooth
    • tooth is_a multi-tissue structure

The term ‘tooth’ is redundant for the ZFA because zebrafish have only one type of tooth:

  • ZFA:
    • ceratobranchial 5 tooth is_a multi-tissue structure

Anatomy Term Tracker

The anatomy ontology is regulary updated to include new terms and developed based on feedback from the community. Requests for changes are submitted to the anatomy term tracker and a summary is forwarded to the teleost-discuss mailing list for community discussion (see instructions on requesting terms for details). Terms are added to the TAO usually within one week, with any comments or suggestions from teleost-discuss incorporated. We invite you to join the teleost-discuss mailing list and contribute to the discussion of terms.

Homology

Homology links are important in the use of multi-species ontologies to define homology relations between different terms in the ontology, and because homology is not implied if the same term is used in annotations for different species. Terms in the anatomy ontology are defined based on structural similarity, and it cannot be assumed that this similarity is due to common ancestry. For example, zebrafish and humans both possess a frontal bone; however, there is evidence that the zebrafish frontal bone is homologous to the human parietal bone. Our use of the homologous_to relation between entities that are homologues will help clarify the identity of such similarly named but nonhomologous bones.

We have developed a method for homology designation by recording homology statements outside of the ontology, as an annotation with attribution and evidence codes. Homology statements are hypotheses, and users of our database will have the option of viewing competing hypotheses of homology when they occur.